Smart Manufacturing lab is an inter-disciplinary research lab focused on IT enabled Design and Manufacturing at IIITDM Kancheepuram. This lab develops IT products relevant to Industry 4.0 platform technologies such as Additive Manufacturing, Internet of Things, Augmented Reality and Virtual Reality, Cloud Manufacturing, Digital Thread and Digital Twin. The main objective is to study the interoperability issues in disparate information systems of life cycle, value chain and enterprise domain in an extended manufacturing enterprise. Further, the centre undertakes research aimed at bridging the gap between the human and digital world by interfacing human cognitive capabilities into IoT systems. Distributed manufacturing paradigms are vital to decentralize the manufacturing and the main the challenge we address is to evolve novel product architectures catering to need of such smart manufacturing systems. For these objectives, we have teamed up with major universities and leading industries for collaborative development of the technology and transfer to industry in the end.